Blood Transfusion: A Basic Text (WHO Regional Publications by WHO Regional Office for the Eastern Mediterranean

By WHO Regional Office for the Eastern Mediterranean

A realistic common sense advisor to the effective association and administration of blood transfusion providers. built in the course of a chain of workshops held within the jap Mediterranean zone, the handbook goals to assist new providers cash in on worldwide event whereas encouraging verified prone to improve their practices and rules based on fast advances in blood banking expertise. info responds to the distinctive wishes and prerequisites visible in japanese Mediterranean international locations. Adopting a problem-oriented method, the guide concentrates on 3 components liable for such a lot weaknesses and such a lot blunders within the region's blood transfusion companies: association and administration, blood donor motivation and blood assortment, and caliber coverage. Case experiences and examples of kingdom reports are used in the course of the textual content to facilitate realizing of day by day techniques in addition to basic ideas. The center of the handbook comprises 3 distinctive chapters protecting the association and administration of blood transfusion companies, the recruitment of donors and blood assortment, and the total variety of administration and operational platforms wanted for caliber insurance.

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Additional info for Blood Transfusion: A Basic Text (WHO Regional Publications Eastern Mediterranean Series)

Sample text

However, other than proving that a case is myeloid, immunophenotyping is not essential for the application of the WHO classification. The WHO classification is hierarchical. Cases are assigned to categories in the order shown in the following paragraphs. Therapy-related AML The 2001 WHO classification recognized two broad groups of therapy-related AML although some overlap occurs [13–15]. In the 2008 classification the two categories have been amalgamated. g. g. lomustine), platinum-based agents (carboplatin, cisplatin) and exposure to radiation is characterized by a latent phase of 5–10 years, preceding MDS, trilineage myelodysplasia and an association with abnormalities of chromosomes 5 and 7 (–5, 5q–, –7, 7q–) and with complex chromosomal abnormalities.

Mast cell disorders are a group by themselves rather than being recognized as a MPN in the 2001 classification but in the 2008 classification are grouped with other MPN. With advancing knowledge of the molecular mechanisms underlying chronic haematological neoplasms, the three broad groups of MPN, MDS and MDS/MPN may prove constricting. Cases with the same molecular abnormality will sometimes fall into the MPN category and sometimes into the MDS/MPN group. The next decade is likely to see a reappraisal of the basis of our classifications.

2005). Therapy-related leukemia: clinical characteristics and analysis of new molecular risk factors in 96 adult patients. Leukemia, 19, 1919–1928. 16 Bloomfield CD, Archer KJ, Mrozek K, Lillington DM, Kaneko Y, Head DR et al. (2002). 11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop. Genes, Chromosomes Cancer, 33, 331–345. 17 Slovak ML, Bedell V, Popplewell L, Arber DA, Schoch C, Slater R et al. (2002).

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