Cellular and Molecular Neurophysiology, Third Edition by Constance Hammond

By Constance Hammond

Cellular and Molecular Neurophysiology, 3rd Edition, is the hot, completely revised version of the single present, tested, and authoritative textual content targeting the mobile and molecular body structure of nerve cells. formerly titled Cellular and Molecular Neurobiology, the hot name higher displays this concentration. This model comprises eighty% new or up-to-date material.

Fifteen appendices describing neurobiological options are interspersed within the textual content. Now in complete colour all through, the e-book has over four hundred conscientiously chosen and developed illustrations. It comprises an teacher site with the entire photographs in digital layout, plus extra fabric. The e-book is speculation pushed instead of simply providing the proof, and the content material is firmly in response to quite a few experiments played via the head specialists within the field.

While protecting the real proof, the publication additionally provides the history for a way researchers arrived at this information to supply a context for the sphere. It promotes a true figuring out of the functionality of nerve cells that's invaluable for practising neurophysiologists and scholars in a graduate-level path at the subject alike.

* eighty% new or up-to-date material
* Fifteen appendices describing neurobiological ideas are interspersed within the text
* Now in complete colour all through, with greater than four hundred rigorously chosen and developed illustrations
* presents an teacher web site with all of the photographs in digital structure, plus extra fabric

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Extra info for Cellular and Molecular Neurophysiology, Third Edition

Example text

Pour la Science, November, 84–94, with permission. by gap junctions and desmosomes, forming a ‘palisade’ between neurons and vascular endothelial cells. The space between the layer of astrocyte end feet and the endothelial cells is about 40–100 nm and is occupied by a basal lamina. Astrocytes also send processes to the external surface of the central nervous system where the astrocyte end feet, together with the basal lamina that they produce, form the ‘glia limitans externa’, which separates the pia mater from the nervous tissue.

This is especially clear for the case of glutamate: astrocytes have an enormous capacity to take up this transmitter, presumably reflecting the abundance of this transmitter and the toxicity to neurons of high glutamate concentrations. Besides their role in transmitter clearance from the synaptic cleft (by recapture), astrocytes play a role in the 24 2. NEURON–GLIAL CELL COOPERATION synthesis of transmitters and particularly glutamate and GABA. 13), glutamine is formed from glutamate. Glutamine is then uptaken by neurons and transformed back in glutamate.

28 2. 3 SCHWANN CELLS ARE THE GLIAL CELLS OF THE PERIPHERAL NERVOUS SYSTEM; THEY FORM THE MYELIN SHEATH OF AXONS OR ENCAPSULATE NEURONS There are three types of Schwann cell: • those forming the myelin sheath of peripheral myelinated axons (myelinating Schwann cells); • those encapsulating non-myelinated peripheral axons (non-myelinating Schwann cells); those that encapsulate the bodies of ganglion cells (nonmyelinating Schwann cells or satellite cells). 1 Myelinating Schwann cells make the myelin sheath of peripheral axons Along an axon, several Schwann cells form successive segments of the myelin sheath.

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