By Carolina Witchmichen Penteado Schmidt, Fabiana Gatti de Menezes
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Additional resources for Drug Therapy and Interactions in Pediatric Oncology: A Pocket Guide
A marked peak for ALL in early childhood has appeared in Kuwait . Azerbaijan and Kazakhstan have had some declines in childhood cancer mortality over recent years, mainly leukemias, but their childhood cancer mortality rates remain higher than those in more developed countries . 14 %) . 6 Childhood Cancer in Central America One large study carried out in Central America found that the 3-year survival rate of childhood cancer ranged from 48 to 62 %, with pronounced variations across eight national hospitals in seven countries .
Non-Hodgkin Lymphoma (NHL) Biopsy of bone marrow aspirate, lumbar puncture, pleural or peritoneal fluid sampling, immunohistochemistry, flow cytometry . 3 Major oncological diseases in children Diseases Main diagnostics Hodgkin Biopsy, lumbar puncture, computed Lymphoma (HL) tomography (CT) scan and magnetic resonance image . Differential diagnosis between classic and lymphocytic predominance is done by immunohistochemistry . (continued) Accounts for 6 % of total childhood cancers, and is frequently high grade.
83] 24 Chapter 1. 7 Childhood Cancer in Oceania In Oceania, the risk of Burkitt’s lymphoma is highest in Papua New Guinea, due to the association of this lymphoma with infection by the Epstein-Barr virus and the intense stimulation of immunity caused by malaria. In children who have immunodeficiency, the Epstein-Barr virus is probably also implicated in Hodgkin disease, non-Hodgkin lymphomas, nasopharyngeal carcinoma, and other cancers [72, 73]. Among the predominantly white populations of Oceania, the incidence of Hodgkin lymphoma appears to be lowest in colder regions of higher latitude [73, 84].