Endovascular Therapy: Principles of Peripheral Interventions by Alan B. Lumsden, Peter H. Lin, Ruth L. Bush MD, Changyi

By Alan B. Lumsden, Peter H. Lin, Ruth L. Bush MD, Changyi Chen, Michael E. DeBakey

While you're one of many many physicians from varied strong point disciplines who practice endovascular interventions then this sensible reference might help you to advance your endovascular talents and surround them into day-by-day practice.

Endovascular remedy covers every thing you must learn about growing an endovascular software, akin to imaging, catheter and gadget stock, nursing aid, and technician support.

moreover, this booklet offers a easy wisdom of the pathophysiology of vascular sickness, interventional recommendations, and endovascular modalities of varied disorder different types. each one person ailment and endovascular treatment is mentioned and emphasis is put on the appropriate problems linked to the extensive spectrum of endovascular interventions.

additionally incorporated are step by step courses to method behavior, information and tips, approach particular gear lists, and suggested submit approach orders and stick to up.

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Additional resources for Endovascular Therapy: Principles of Peripheral Interventions

Example text

Most current understanding and practice is derived by extrapolating data from PCI to peripheral interventions. Anticoagulant agents can be broadly divided into two categories – antiplatelet agents and inhibitors of the coagulation cascade. 40 Chapter 3 Antiplatelet agents The most commonly used antiplatelet agent remains aspirin (acetylsalicylic acid, ASA). 4,5 Although clinically effective, aspirin is a weak antiplatelet agent, and does not inhibit any of the other routes of platelet activation (thrombin, adenosine diphosphate, epinephrine, and serotonin).

Current work has centered around one study that described the effect of actinomycin D versus bare metal stents. 32 Other problems with actinomycin D are that the drug has a very narrow therapeutic window. Due to its water soluble nature, the pharmacokinetics of the drug are extremely unpredictable, thereby preventing any accurate prediction of drug release and duration of action. The narrow therapeutic window can lead to an increased range of side effects such as local tissue damage, which can result in necrosis of the vessel wall.

Most current understanding and practice is derived by extrapolating data from PCI to peripheral interventions. Anticoagulant agents can be broadly divided into two categories – antiplatelet agents and inhibitors of the coagulation cascade. 40 Chapter 3 Antiplatelet agents The most commonly used antiplatelet agent remains aspirin (acetylsalicylic acid, ASA). 4,5 Although clinically effective, aspirin is a weak antiplatelet agent, and does not inhibit any of the other routes of platelet activation (thrombin, adenosine diphosphate, epinephrine, and serotonin).

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