By E. Erdmann, B. Höfling, A.v. Pölnitz, G. Steinbeck, B.-E. Strauer
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Naturwissenschaften 50:228 12. Griintzig A (1976) Perkutane Dilatation von Coronarstenosen - Beschreibung eines neuen Kathetersystems. Klin Wochenschr 54: 543 13. Karsch KR, Mauser M, Spiel L (1985) Wirkungsmechanismen von intrakoronarem, sublingualem und intravenosem Nifedipine bei Patienten mit instabiler Angina pectoris. In: Meyer l, Erbel R. (eds) Intravenose und intrakoronare Anwendung von Adalat. Springer Verlag Berlin Heidelberg, pp. 114-124 14. Kober G, Vallbracht C, Kaltenbach M (1987) Early and late results after percutaneous transluminal coronary angioplasty compared with bypass operation.
In the process, superoxide (0 2 - ) is produced which may induce damage in the ischemic myocyte. The xanthine activity is elevated in the capillary endothelium and increases as a consequence of the ischemia induced conversion of xanthine dehydrogenase (X - D) to xanthine oxidase. (With permission of the authors Hears DJ et al. in: Acta Physiol Scand 1986. Suppl 548: 65 - 78) 29 of species (20). g. rabbit (21) and pig (22), it seems to be absent. Literature data on xanthine oxidase in human heart are conflicting.
1). Use was made ofa 22 AFTER FIRST PRE PTCA PTCA A Cl. 002 AU Cl. > :r: o 5 10 o 5 10 minutes Fig. 1. Isocratic high pressure liquid chromatographic separation of nucleosides and purine bases from a patient before and after a single transluminal occlusion . hyp = hypoxanthine ; AU = absorption units reversed-phase column. Since nucleotides derived from erythrocytes affected the separation, these compounds had to be removed . We used the method of Chatterjee et al. (8), with some minor differences.