Our Molecular Nature: The Body’s Motors, Machines and by David S. Goodsell

By David S. Goodsell

Molecular Nature is a richly illustrated consultant to the extreme range of molecules which are liable for existence. David Goodsell, writer of the highly-praised booklet, The equipment of existence, has synthesized an unlimited volume of information in a fashion that's available to the overall reader. Molecular Nature examines themes starting from the form of cells to the molecules liable for digestion, immunity, and idea. The author's targeted mixture of medical and inventive abilities make this a readable, stimulating and hugely evocative e-book. About the Author: David Goodsell is within the division of Molecular Biology on the study Institute of Scripps sanatorium in l. a. Jolla, California. His study contains special effects and X-ray crystallography. he's the writer of The equipment of lifestyles (Springer-Verlag, 1992), and his art has been proven at exhibitions on technology and artwork.

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Glucose, however, does not have the taste that consumers prefer, so it is converted to sweeter fructose by application of bacterial d-xylose isomerase. Enzymes are remarkable machines, and like machines of our familiar world, they are often the focus of industrial entrepreneurs . o-Xylose isomerase is but one example. Digestive enzymes have found use in laundry detergents, chewing away nasty stains, and in cleaning solutions for contact lenses. Other digestive enzymes, purified in large quantities from bacteria, curdle milk into cheese.

A similar class of proteinases, termed cysteine proteinases, use the sulfur atom in a cysteine amino acid to perform a cleavage reaction, in place of the oxygen atom in a serine. Tiny digestive compartments inside each of our cells, termed lysosomes, contain the cysteine proteinases cathepsin B and cathepsin H, as well as dozens of other digestive enzymes. Inside lysosomes, old proteins are digested and their amino acids are recycled to build new proteins. Two cysteine proteinases made by plants may be found in the local grocery store.

The difference between a poison and a drug is the identity of the victim. If our own ribosomes are attacked, the compound is a poison; if the smaller ribosomes of bacteria fall victim, the compound will be useful as an antibiotic drug. Chloramphenicol, tetracycline, and streptomycin fall in the latter category, attacking bacterial ribosomes and leaving our larger ribosomes unharmed. Unfortunately, they may also, attack the smaller ribosomes in our mitochondria, leading to unwelcome side effects.

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