Trafficking of GPCRs, 1st Edition by Wu, Guangyu

By Wu, Guangyu

G protein-coupled receptors (GPCRs) constitute the largest superfamily of mobile floor receptors that control numerous phone services. during the last few many years nice development has been made in defining the jobs of intracellular trafficking in controlling the performance of the receptors in addition to within the improvement of assorted human illnesses. This quantity of Progress in Molecular Biology and Translational Science reviews the hot figuring out of GPCR trafficking regulators and molecular mechanisms.

  • Written through destiny leaders within the discomfort field
  • Covers a variety of targets
  • Contains provocative rules approximately GPCR trafficking

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Pierce KL, Premont RT, Lefkowitz RJ. Seven-transmembrane receptors. Nat Rev Mol Cell Biol. 2002;3(9):639–650. 3. Moore CA, Milano SK, Benovic JL. Regulation of receptor trafficking by GRKs and arrestins. Annu Rev Physiol. 2007;69:451–482. 4. Perry SJ, Baillie GS, Kohout TA, et al. Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science. 2002;298(5594):834–836. 5. Nelson CD, Perry SJ, Regier DS, Prescott SM, Topham MK, Lefkowitz RJ. Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins.

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